This icon does not depict an event from the life of Christ or His apostles. Rather, it represents the timeless, eternal, and mystical event being celebrated celestially. The Eucharist is not restricted to a particular time or place.
In this line drawing of the Last or Mystical Suppper Christ is the central figure. St. John the Beloved, the Evangelist, is to Christ's right. As the youngest of the disciples he is depicted without a beard. Judas Iscariot, who betrayed Christ is the third figure from Christ's left. He is dipping his hand into the dish (see Matthew 26:20-25).
This icon depicts the marriage feast where Christ performed His first miracle, that of turning water into fine wine. The bridal couple are shown wearing crowns, a tradition repeated in today's Orthodox wedding service.